The Translational Research in Affective Disorders (TReAD) Lab studies the behavioral and neurobiological determinants of cost/benefit decision-making in healthy individuals, as well as in patients with mental illness. Our research focuses on the neural circuitry that underlies decision-making and how abnormalities in these processes relate to and manifest as core symptoms in affective disorders, like major depressive disorder. To participate in our research, please complete the appropriate interest survey
Glutamate/Ketamine Study
The TReAD Lab is currently conducting research investigating neuroimaging markers of response to ketamine.
This study might be a good fit if you are:
- Between the ages of 18-65
- Right-handed
- Willing and able to complete fMRI scans
- Fulfill one of the following criteria:
- Currently experiencing a depressive episode
- Not diagnosed with any mood disorders
- Not taking psychotropic medications
What does the study entail?
- Screening visit(s)
- One infusion of study drug or placebo
- Multiple follow-up visits
- Five MRI scans
- Compensation is provided for your time
If you are interested in participating, please complete our INTEREST SURVEY.
Brain Stimulation Study
The TReAD Lab is currently conducting a research study to learn about motivation and decision-making.
This study might be a good fit if you are:
- Between the ages of 18-40
- Right-handed
- Not taking psychotropic medications
- No personal or family history of seizures
What does the study entail?
- fMRI scan
- Transcranial magnetic stimulation (TMS)/Temporal Interference (TI)
- Computer tasks
- Clinical interview
- Self-report surveys
- Compensation is provided for your time
If you are interested in participating, please complete our INTEREST SURVEY
Behavioral Activation Therapy Study
The Child and Adolescent Mood Program (CAMP) is currently conducting research investigating a type of treatment called Behavioral Activation (BA) Therapy with adolescents.
This study might be a good fit if your teen is:
- Between the ages of 15-17
- Right-handed
- Willing and able to complete fMRI scans
- Not taking psychotropic medications for depression
- Fulfilling one of the following criteria:
- Diagnosed with Major Depressive Disorder (MDD)
- Not diagnosed with any mood disorder
What does the study entail?
- A screening visit
- 21 days of cellphone surveys
- 16 free BA therapy sessions (scheduled weekly)
- Up to five fMRI visits (three outside of regularly scheduled therapy sessions)
- Compensation is provided for your time
To learn more, please visit the study website.
Stress and Anhedonia
The TReAD Lab is currently conducting a research study to investigate biomarkers of anhedonia.
This study might be a good fit if you are:
- Between the ages of 18 - 65
- Right-handed
- Willing and able to complete fMRI scans
- Not taking any psychotropic medications
- Fulfilling one of the following criteria:
- Currently experiencing a lack of interest or pleasure in things you would normally enjoy
- Not experiencing abnormal mood
What does the study entail?
- A screening visit
- 28 days of cellphone surveys
- A blood-draw
- Multiple brain scans
- Compensation is provided for your time
If you are interested in participating, please complete our INTEREST SURVEY.